The win was the first home win over Middle Tennessee since 1989 and first overall since 2011.
It is the first time in the program's FBS history they have been a preseason favorite.
All seven returning starters on offense picked up an All-Conference selection.
NCAA Football: Western Kentucky faces Marshall at Houchens Industries-L.T. Smith Stadium.
Joe Brown stopped Nathan Marcus a yard shy of the goal line on a two-point conversion attempt with 33 seconds left to preserve Western Kentucky's 14-12 victory over Vanderbilt on Thursday night.
2014 Second Team All-Conference USA (Phil Steele)
2014 Honorable Mention All-Conference USA
Career Game Highs:
Before WKU: Holt tacked on 61 tackles for the City College of San Francisco and coach George Rush including 32 solo tackles, the second-highest mark on the squad. He added 7.5 tackles for loss with 1.5 sacks as well as a forced fumble and an interception. Holt was rated as the No. 11 inside linebacker prospect among all junior college players by 247Sports.com.
HS/Misc.: Holt played quarterback and linebacker at Seattle Prep for coach D.R. Clawson and was the Co-Defensive MVP of the Metro League Mountain Division in 2010, as well as first-team All-Metro as quarterback and linebacker. He was also named first-team 3A All-State by the Associated Press and is the son of current WKU defensive coordinator Nick Holt.